College of Pharmacy | Biopharmaceutical Sciences
College of Medicine | Ophthalmology and Visual Science
College of Engineering | Bioengineering | Chemical Engineering
UIC | OVCR | Research Integrity
Jamie Rayahin
833 S. Wood Street (MC 865)
College of Pharmacy Building, Room 359
Chicago, IL 60612-7231
(312) 996-9765 Lab

NIH ARRA REU/Rotation Student: June 2010 - August 2010
Pharm.D/Ph.D. Student : August. 2010 - current

Department of Biopharmaceutical Sciences

Project: Hyaluronan as a regulator of macrophage function

Pharm.D. Student, University of Illinois at Chicago, 2010 - current
B.S. Biological Sciences, University of Illinois at Chicago, 2010
Awards
  1. 2011: Riback Research Fellowship
  2. 2011: Polymers in Medicine and Biology (ACS Symposium) Poster Award, 3rd Place
  3. 2012: Riback Research Felowship
  4. 2012-2014: Chancellor's Graduate Research Fellowship
  5. 2013: W.E. van Doren Scholar
  6. 2013: College of Medicine Research Forum, Honorable Mention
  7. 2014-2015: Chicago Biomedical Consortium Scholar
  8. 2014: The Protein Society, Best Poster Award
Peer-Reviewed Manuscripts
  1. Chang J, Schul W, Butters T, Yip A, Liu B, Goh A, Lakshminarayanab S, Alonzi D, Reinkensmeier G, Pan X., Qu X, Weidner J, Wang L, Yu W, Borune N, Kinch M, Rayahin JE, Moriarty R, Xu X, Shi P, Guo J, Block T. Combination of alpha-glucosidase inhibitor and ribavirin for the treatment of dengue virus infection in vitro and in vivo. Antiviral Research. 2011. Jan; 89(1):26-34.
  2. Kim M, Rooper L, Xie J, Rayahin JE, Burdette JE, Kajdacsy-Balla AA, Barbolina MV. The lymphotactin receptor is expressed in epithelial ovarian carcinoma and contributes to cell migration and proliferation. Molecular cancer research : MCR, 10(11): 1419-29, 2012. DOI:10.1158/1541-7786.MCR-12-0361 PMID: 22964431
  3. Rayahin JE, Buhrman JS, Gemeinhart RA. Hybrid Nanocrystals: University of Kentucky US 2006/0280680A1. Expert Opinion on Therapeutic Patents, 22(3): 341-348, 2012. DOI & Pubmed
  4. Buhrman JS, Rayahin JE, Köllmer M, Gemeinhart RA. In-house preparation of hydrogels for batch affinity purification of glutathione S-transferase tagged recombinant proteins. BMC Biotechnology, 12: 63, 2012. DOI & Pubmed
  5. Buhrman JS, Cook LC, Rayahin JE, Federle MJ, Gemeinhart RA. Proteolytically activated anti-bacterial hydrogel microspheres. Journal of Controlled Release, 171(3): 288-295. DOI & Pubmed
  6. Buhrman JS, Cook LC, Rayahin JE, Federle MJ, Gemeinhart RA. Active, soluble recombinant melittin purified by extracting insoluble lysate of Escherichia coli without denaturation. Biotechnology Progress, 29(5): 1150-1157, 2013. DOI & Pubmed
  7. Rayahin JE, Buhrman JS, Gemeinhart RA. Melittin, as a glutathione S-transferase fusion protein, maintains anti-inflammatory properties while diminishing toxicity, European Journal of Pharmaceutical Sciences, 65(1): 112-121, 2014. DOI & Pubmed
  8. Rayahin JE, Buhrman JS, Zhang Y, Koh TJ, Gemeinhart RA. High and low molecular weight hyaluronic acid differentially influence macrophage activation, ACS Biomaterials Science and Engineering. 2015,1(7): 481-493, 2015. DOI & Pubmed
  9. Zhang Y, Buhrman JS, Liu Y, Rayahin JE, Gemeinhart RA. Reducible Micelleplexes are Stable Systems for Anti-miRNA Delivery in Cerebrospinal Fluid, Molecular Pharmaceutics, online ahead of print, 2016. DOI & Pubmed
Book Chapters
  1. Rayahin JE, Gemeinhart RA. Activation of Macrophages in Response to Biomaterials. In: Kloc M (ed) Macrophages - Origin, functions and biointervention. Results and problems in cell differentiation. Springer, New York. In press.
Patents and Disclosures
  1. Gemeinhart RA, Buhrman JS, Rayahin JE. Hydrogels for Delivery of Therapeutic Polypeptides, US 9,457,101B2 (October 4, 2016). USPTO
Abstracts and Proceedings
  1. Kim M., Kajdacsy-Balla A., Rooper L., Rayahin J., Barbolina M. B49 Role of fractalkine/fractalkine receptor signaling in progression of epithelial ovarian carcinoma. MRS-AACR Joint Conference on Metastasis, Philadelphia, PA (September 2010).
  2. Zhang Y, Rayahin JE, Gemeinhart RA. Use of Pendent Charge with Hydrogels to Modulate Matrix-Metalloprotease-Stimulated Drug Delivery, Polymers in Medicine and Biology, Santa Rosa, CA (September 2011).
  3. Rayahin JE, Gemeinhart RA. Surface Modification of Microparticles for Targeted Delivery. College of Pharmacy Research Day, Chicago, IL (February 2012).
  4. Buhrman JS, Rayahin JE, Köllmer M, Gemeinhart RA. Using the glutathione s-transferase/glutathione interaction as a protein anchor in a controlled release delivery system for cancer treatment. 2012 College of Medicine Research Forum, Chicago, IL (November 2012)
  5. Buhrman JS, Rayahin JE, öKllmer M, Gemeinhart RA. Modeling the use of the glutathione s-transferase:-glutathione interaction as an anchor in a protein delivery system for cancer treatment., College of Pharmacy Research Day, Chicago, IL (February 2013).
  6. Rayahin JE, Buhrman JS, Gemeinhart RA. Degradable hyaluronic acid/interleukin-1 receptor antagonist wafers for osteoarthritis, College of Pharmacy Research Day, Chicago, IL (February 2013).
  7. Rayahin JE, Buhrman JS, Gemeinhart RA. Melittin fusion protein and hyaluronic acid have augmented anti-inflammatory properties when combined. College of Medicine Research Day, Chicago, IL (November 2013).
  8. Rayahin JE, Chmiel JS, Almagor O, Belisle L, Chang AH, Moisio K, Hayes KW, Zhang Y, Sharma L. Factors Associated with Two-Year Pain Experience Outcome in Knee Osteoarthritis. American College of Rheumatology Meeting, San Diego, CA (October 2013).
  9. Rayahin JE, Chmiel JS, Almagor O, Belisle L, Chang AH, Moisio K, Hayes KW, Zhang Y, Sharma L. Factors Associated with Two-Year Pain Experience Outcome in Knee Osteoarthritis. College of Medicine Research Day, Chicago, IL (November 2013).
  10. Buhrman JS, Rayahin JE, Gemeinhart RA. Recombinant Melittin Protein Therapy for the Treatment of High Grade Astrocytoma. College of Medicine Research Day, Chicago, IL (November 2013).
  11. Buhrman JS, Rayahin JE, Gemeinhart RA. Recombinant Melittin as Protein Therapy for Treatment of High Grade Astrocytoma. College of Pharmacy Research Day, Chicago, IL (March 2014).
  12. Rayahin JE, Buhrman JS, Gemeinhart RA. Melittin Fusion Protein and Hyaluronic Acid Have Augmented Anti-Inflammatory Properties When Combined. College of Pharmacy Research Day, Chicago, IL (March 2014).
  13. Rayahin JE, Buhrman JS, Gemeinhart RA. Recombinant melittin protein loaded microspheres for treatment of high-grade astrocytoma. AICHE Midwest Regional Conference (Platform Talk), Chicago, IL (March 2014).
  14. Buhrman JS, Rayahin JE, Gemeinhart RA. Polymeric modulation of immune cell function. AICHE Midwest Regional Conference (Platform Talk), Chicago, IL (March 2014).
  15. Buhrman JS, Rayahin JE, Gemeinhart RA. Recombinant melittin protein therapy for treatment of high grade astrocytoma. American Physician Scientists Association. Chicago, IL (April 2014).
  16. Buhrman JS, Rayahin JE, Gemeinhart RA. Delivering Recombinant Melittin for Treatment of High Grade Astrocytoma. International Symposium on Controlled Release of Bioactive Materials, Chicago, IL (July 2014).
  17. Rayahin JE, Buhrman JS, Gemeinhart RA. Melittin-GST fusion protein and hyaluronic acid have augmented anti-inflammatory properties when Combined. International Symposium on Controlled Release of Bioactive Materials, Chicago, IL (July 2014).
  18. Buhrman JS, Rayahin JE, Zhang Y, Tang MY, Gemeinhart RA. Biologically responsive recombinant protein anchors for macromolecular drug delivery. 28th Annual Symposium of the Protein Society, San Diego, CA (July 2014).
Input Richard A. Gemeinahrt: BPS, College of Pharmacy in Other
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