College of Pharmacy | Biopharmaceutical Sciences
College of Medicine | Ophthalmology and Visual Science
College of Engineering | Bioengineering | Chemical Engineering
UIC | OVCR | Research Integrity
Yu Zhang, M.S., Ph.D.

Ph.D. Rotation: Aug. 2010 - Dec. 2010
Ph.D. Student: Jan. 2011 - Aug. 2015

Department of Biopharmaceutical Sciences

Thesis Title: Anti-miRNA Delivery Systems Based on Self-assembled Nanostructures
Defense Date: August 18, 2015

B.S., Life Sciences, Northeast Forestry Unversity, 2007
M.S., Botanical Drugs, Northeast Forestry Unversity, 2010
Ph.D., Pharmaceutics, University of Illinois, 2015

Current Position: Research Scientist, Fresenius Kabi USA
Awards
  1. 2003:First Class Scholarship
  2. 2004:First Class Scholarship
  3. 2005:First Class Scholarship
  4. 2006:First Class Scholarship
  5. 2007:First Class Scholarship
  6. 2006: Heilongjiang Provincial Merit Student
  7. 2007: Outstanding Graduate of Northeast Forestry University
  8. 2010-2011: University Fellowship
  9. 2011: Polymers in Medicine and Biology (ACS Symposium) Poster Award, 3rd Place
  10. 2013-2014: University Felowship
  11. 2013: W.C. and May Preble Deiss Award for Biomedical Research
  12. 2014-2015: Dean's Scholar
  13. 2014: The Protein Society, Best Poster Award
  14. 2014: University of Illinois at Chicago, Image of Research Competition, Honorable Mention
  15. 2015: College of Pharmacy Research Day, Predoctoral Poster Award, 2nd Place
  16. 2015: Charles Wesley Petranek Memorial Scholarship
Peer-Reviewed Manuscripts
  1. Zu YG, Yuan S, Zhao XH, Zhang Y, Zhang XN. Preparation, activity and targeting ability evaluation in vitro on folate mediated epigallocatechin-3-gallate albumin nanoparticles. Acta Pharmaceutica Sinica, 2009, 44 (5): 525-531.
  2. Zhang Y, Liu T. Extracting technique and antioxidant activity of polyphenols from testa of Quercus Mongolica Fischer. Bulletin of Botanical Research, 2009, 29 (6): 711-716.
  3. Zu YG, Zhang Y, Zhao X, Liu Y, Jiang R. Optimization of the preparation process of vinblastine sulfate (VBLS) loaded folate-conjugated bovine serum albumin (BSA) nanoparticles for tumor-targeted drug delivery using response surface methodology (RSM). International Journal of Nanomedicine. 2009:4 321-333
  4. Li QY, Yao L, Zu YG, Lv H, Zhang Y. Cytotoxicity and Topo I-targeting activity of substituted 10- nitrogenous heterocyclic aromatic group derivatives of SN-38. European Journal of Medicinal Chemistry. 2010, 45(7): 3200-3206
  5. Zhang Y, Gemeinhart RA. Improving Matrix Metalloproteinase-2 Specific Response of a Hydrogel System using Electrophoresis. International Journal of Pharmaceutics, 429(1-2): 31-37, 2012. DOI & Pubmed
  6. Köllmer M, Buhrman JS, Zhang Y, Gemeinhart RA. Markers Are Shared Between Adipogenic and Osteogenic Differentiated Mesenchymal Stem Cells. Journal of Developmental Biology and Tissue Engineering. 5(2): 18-25, 2013. DOI
  7. Zhang Y, Wang ZJ, Gemeinhart RA. Progress in MicroRNA Delivery, Journal of Controlled Release, 172(3): 962-974, 2013.DOI & Pubmed
  8. Zhang Y, Kölmer M, Buhrman JS, Tang MY, Gemeinhart RA. Arginine-rich, Cell Penetrating Peptide-microRNA Inhibitor Complexes Decrease Glioblastoma Migration Potential, Peptides, 58(1): 83-90, 2014. DOI & Pubmed
  9. Zhang Y, Liu Y Sen S, Král P, Gemeinhart RA. Charged Group Surface Accessibility Determines Micelleplexes Formation and Cellular Interaction, Nanoscale, 7(17): 7559-7564,2015. DOI & Pubmed
  10. Rayahin JE, Buhrman JS, Zhang Y, Koh TJ, Gemeinhart RA. High and low molecular weight hyaluronic acid differentially influence macrophage activation, ACS Biomaterials Science and Engineering. 2015,1(7): 481-493, 2015. DOI & Pubmed
  11. Zhang Y, Buhrman JS, Liu Y, Rayahin JE, Gemeinhart RA. Reducible Micelleplexes are Stable Systems for Anti-miRNA Delivery in Cerebrospinal Fluid, Molecular Pharmaceutics, 13(6): 1791-1799, 2016. DOI & Pubmed
Patents and Disclosures
  1. Gemeinhart RA, Zhang Y. Method of Electrophoretic Removal of Unreacted Groups from Materials. Disclosed (DF134; 3/13/2012) and provisional patent application submitted (03/08/2012).
Abstracts and Proceedings
  1. Zhang Y, Rayahin JE, Gemeinhart RA. Use of Pendent Charge with Hydrogels to Modulate Matrix-Metalloprotease-Stimulated Drug Delivery, Polymers in Medicine and Biology, Santa Rosa, CA (September 2011).
  2. Zhang Y, Gemeinhart RA, Matrix Metalloproteinase-2 Activable Charged Hydrogel Drug Delivery System. 3rd Annual Symposium of the Illinois Chapter of the Controlled Release Society: Recent Advances in Nanotechnology for Cancer Therapy. Chicago, IL (August 2011).
  3. Zhang Y, Gemeinhart RA. Optimization of Matrix Metalloprotease-2 Responsive Hydrogel Drug Delivery System. College of Pharmacy Research Day, Chicago, IL (February 2012).
  4. Zhang Y, Gemeinhart RA. Electrophoretic Disruption of Nonspecific Peptide Interactions with MMP-Sensitive Hydrogels. International Symposium on Controlled Release of Bioactive Materials, Quebec City, QC (July 2012).
  5. Köllmer M, Buhrman JS, Zhang Y, Gemeinhart RA. Markers Are Shared Between Adipogenic and Osteogenic Differentiated Mesenchymal Stem Cells, College of Pharmacy Research Day, Chicago, IL (February 2013).
  6. Tang MY, Nwanah L, Zhang Y, Gemeinhart RA. Multiscale Drug Delivery System: Pluronic F-127 Micelles Encapsulated in PEGDA Hydrogels. College of Pharmacy Research Day, Chicago, IL (February 2013).
  7. Zhang Y, Köllmer M, Tang MY, Ramirez EA, Gemeinhart RA. Arginine-rich Cell Penetrating Peptide-microRNA Inhibitor Complexes Decrease Glioblastoma Migration Potential. College of Pharmacy Research Day, Chicago, IL (February 2013).
  8. Zhang Y, Köllmer M, Tang MY, Gemeinhart RA. Arginine-rich Cell Penetrating Peptide-microRNA Inhibitor Complexes Decrease Glioblastoma Migration Potential. International Symposium on Controlled Release of Bioactive Materials, Honolulu, HI (July 2013).
  9. Tang MY, Nwanah L, Zhang Y, Köllmer M, Gemeinhart RA. Multiscale Drug Delivery System: Micelles Encapsulated in Hydrogels. International Symposium on Controlled Release of Bioactive Materials, Honolulu, HI (July 2013).
  10. Zhang Y, Liu Y, Buhrman JS, Gemeinhart RA. Redox Responsive Micelles for Codelivery of Drugs and Silencing RNAs. College of Pharmacy Research Day, Chicago, IL (March 2014).
  11. Tang MY, Nwanah L, Zhang Y, Nguyen T, Gemeinhart RA. Multiscale Drug Delivery System: Pluronic F-127 Micelles Encapsulated in PEGDA Hydrogels. College of Pharmacy Research Day, Chicago, IL (March 2014).
  12. Zhang Y, Liu Y, Gemeinhart RA. Exploring Redox Responsive Polymeric Drug Delivery System for Codelivery of Hydrophobic Drug and Silencing RNAs. Midwest Pharmaceutics Graduate Student Meeting, Chicago, IL (June 2014).
  13. Tang MY, Nwanah L, Zhang Y, Gemeinhart RA. Multiscale Drug Delivery System: Micelles Encapsulated in Hydrogels. International Symposium on Controlled Release of Bioactive Materials, Chicago, IL (July 2014).
  14. Zhang Y, Liu Y, Buhrman JS, Gemeinhart RA. Exploring Redox Responsive Polymeric Drug Delivery System for Codelivery of Hydrophobic Drug and Silencing RNAs. International Symposium on Controlled Release of Bioactive Materials, Chicago, IL (July 2014).
  15. Buhrman JS, Rayahin JE, Zhang Y, Tang MY, Gemeinhart RA. Biologically responsive recombinant protein anchors for macromolecular drug delivery. 28th Annual Symposium of the Protein Society, San Diego, CA (July 2014)
  16. Buhrman JS, Rayahin JE, Zhang Y, Tang MY, Gemeinhart RA. Biologically responsive recombinant protein anchors for macromolecular drug delivery. Annual Chicago Biomedical Consortium Meeting, Chicago, IL (October 2014).
  17. Rayahin JE, Zhang Y, Buhrman JS, Gemeinhart RA. Hyaluronan as a regulator of macrophage function: implications for inflammation and angiogenesis. Annual Meeting of the Society for Glycobiology, Honolulu, HI (November 2014).
  18. Buhrman JS, Rayahin JE, Zhang Y, Tang MY, Gemeinhart RA. Biologically Responsive Recombinant Protein Anchors for Macromolecular Drug Delivery. College of Medicine Research Day, Chicago, IL (November 2014).
  19. Zhang Y, Liu Y, Gemeinhart RA. Charged Group Surface Accessibility Determines Micelleplexes Formation and Cellular Interaction. RNA Nanotechnology Gordon Research Conference (February 2015).
  20. Rayahin JE, Zhang Y, Buhrman JS, Tang MY, Gemeinhart RA. Hyaluronan as a regulator of macrophage function: implications for inflammation and angiogenesis. College of Pharmacy Research Day, Chicago, IL (February 2015).
  21. Tang MY, Zhang Y, Rayahin JE, Gemeinhart RA. Understanding Hydrogel Properties to Release Intact Micelles. College of Pharmacy Research Day, Chicago, IL (February 2015).
  22. Buhrman JS, Rayahin JE, Zhang Y, Tang MY, Gemeinhart RA. Recombinant protein immobilization and controlled-release mediated by versatile, non-covalent protein anchor. College of Pharmacy Research Day, Chicago, IL (February 2015)
  23. Zhang Y, Liu Y, Buhrman JS, Gemeinhart RA. Controlling miRNA Micelleplex Formation and Disassembly. College of Pharmacy Research Day, Chicago, IL (February 2015).
Input Richard A. Gemeinahrt: BPS, College of Pharmacy in Other
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