College of Pharmacy | Biopharmaceutical Sciences
College of Medicine | Ophthalmology and Visual Science
College of Engineering | Bioengineering | Chemical Engineering
UIC | OVCR | Research Integrity
Manuscripts | Book Chapters | Patents
Publications Google Scholar Scopus
  1. Liu Y, Zhang Y, Chen S-N, Friesen JB, Nikolic D, Choules MP, McAlpine JB, Lankin DC, Gemeinhart RA, Pauli GF. The Influence of Natural Deep Eutectic Solvents on Bioactive Natural Products: Studying Interactions between a Hydrogel Model and Schisandra chinensis Metabolites, Fitoterapia, in press, 2018. DOI & Pubmed
  2. Zhang Y, Buhrman JS, Liu Y, Rayahin JE, Gemeinhart RA. Reducible Micelleplexes are Stable Systems for Anti-miRNA Delivery in Cerebrospinal Fluid, Molecular Pharmaceutics, 13(6): 1791-1799, 2016. DOI & Pubmed
  3. Jaishankar D, Buhrman JS, Valyi-Nagy T, Gemeinhart RA, Shukla D. Extended release of an anti-heparan sulfate peptide from a contact lens suppresses corneal Herpes Simplex Virus-1 (HSV-1) infection. Investigative Ophthalmology and Visual Science, 57(1): 169-180, 2016. DOI & Pubmed
  4. Lu Y, Chen Y, Gemeinhart RA, Wu W, Li T. Developing nanocrystals for cancer treatment, Nanomedicine, 10(16): 2537-2552, 2015. DOI & Pubmed
  5. Rayahin JE, Buhrman JS, Zhang Y, Koh TJ, Gemeinhart RA. High and low molecular weight hyaluronic acid differentially influence macrophage activation, ACS Biomaterials Science and Engineering, 1(7): 481-493, 2015. DOI & Pubmed
  6. Zhang Y, Liu Y Sen S, Král P, Gemeinhart RA. Charged Group Surface Accessibility Determines Micelleplexes Formation and Cellular Interaction, Nanoscale, 7(17): 7559-7564, 2015. DOI & Pubmed
  7. Rayahin JE, Buhrman JS, Gemeinhart RA. Melittin, as a glutathione S-transferase fusion protein, maintains anti-inflammatory properties while diminishing toxicity, European Journal of Pharmaceutical Sciences, 65(1): 112-121, 2014. DOI & Pubmed
  8. Zhang Y, Köllmer M, Buhrman JS, Tang MY, Gemeinhart RA. Arginine-rich, Cell Penetrating Peptide-microRNA Inhibitor Complexes Decrease Glioblastoma Migration Potential, Peptides, 58(1): 83-90, 2014. DOI & Pubmed
  9. Zellander A, Zhao H, Kotecha M, Low, K-B, Gemeinhart RA, Wardlow M, Abiade J, Cho M. Characterization of pore structure in biologically functional Poly(2-hydroxyethyl methacrylate)-poly(ethylene glycol) diacrylate (PHEMA-PEGDA), PLOS One, 9(5): e96709, 2014. DOI & Pubmed
  10. Sharma V, Köllmer M, Szymusiak M, Nitsche LC, Gemeinhart RA, Liu Y. Toroidal-spiral particles for co-delivery of anti-VEGFR-2 antibody and irinotecan-a potential implant to hinder recurrence of glioblastoma multiforme, Biomacromolecules, 15(3): 756-762, 2014. DOI & Pubmed
  11. Zhang H, Wang X, Dai W, Gemeinhart RA, Zhang Q, Li T. Pharmacokinetics and Treatment Efficacy of Camptothecin Nanocrystals on Lung Metastasis. Molecular Pharmaceutics. 11(1): 226-233, 2013. DOI & Pubmed
  12. Zhang Y, Wang ZJ, Gemeinhart RA. Progress in MicroRNA Delivery, Journal of Controlled Release, 172(3): 962-974, 2013. DOI & Pubmed
  13. Buhrman JS, Cook LC, Rayahin JE, Federle MJ, Gemeinhart RA. Active, soluble recombinant melittin purified by extracting insoluble lysate of Escherichia coli without denaturation. Biotechnology Progress, 29(5): 1150-1157, 2013. DOI & Pubmed
  14. Köllmer M, Popescu C, Manda P, Zhou L, Gemeinhart RA. Stability of Benzocaine Formulated in Commercial Oral Disintegrating Tablet Platforms. AAPS PharmSciTech, 14(4): 1333-1340, 2013. DOI & Pubmed
  15. Hollis CP, Weiss HL, Leggas M, Evers BM, Gemeinhart RA, Li T. Biodistribution and bioimaging studies of hybrid paclitaxel nanocrystals: Lessons learned of the EPR effect and image-guided drug delivery. Journal of Controlled Release, 172(1): 12-21, 2013. DOI & Pubmed
  16. Buhrman JS, Cook LC, Rayahin JE, Federle MJ, Gemeinhart RA. Proteolytically activated anti-bacterial hydrogel microspheres. Journal of Controlled Release, 171(3): 288-295. DOI & Pubmed
  17. Hollis CP, Weiss HL, Evers BM, Gemeinhart RA, Li T. In Vivo Investigation of Hybrid Paclitaxel Nanocrystals with Dual Fluorescent Probes for Cancer Theranostics. Pharmaceutical Research, 31(6): 1450-1459, 2014. . DOI & Pubmed
  18. Köllmer M, Buhrman JS, Zhang Y, Gemeinhart RA. Markers Are Shared Between Adipogenic and Osteogenic Differentiated Mesenchymal Stem Cells. Journal of Developmental Biology and Tissue Engineering. 5(2): 18-25, 2013. DOI & Pubmed
  19. Zellander A, Gemeinhart RA, Djalilian AR, Makhsous M, Sun S, Cho MR. Desiging a Gas Foamed Scaffold for Keratoprosthesis. Material. Science and Engineering C-Materials for Biological Applications, 33(6): 3396-3406, 2013. DOI & Pubmed
  20. Buhrman JS, Rayahin JE, Köllmer M, Gemeinhart RA. In-house preparation of hydrogels for batch affinity purification of glutathione S-transferase tagged recombinant proteins. BMC Biotechnology, 12(1): 63, 2012. DOI & Pubmed
  21. Ross AE, Tang MY, Gemeinhart RA. Effects of Molecular Weight and Loading on Matrix Metalloproteinase-2 Mediated Release from Poly(Ethylene Glycol) Diacrylate Hydrogels. The AAPS Journal, 14(3): 482-490, 2012. DOI & Pubmed
  22. Zhang Y, Gemeinhart RA. Improving Matrix Metalloproteinase-2 Specific Response of a Hydrogel System using Electrophoresis. International Journal of Pharmaceutics, 429(1-2): 31-37, 2012. DOI & Pubmed
  23. Köllmer M, Keskar V, Hauk TG, Collins JM, Russell B, Gemeinhart RA. Stem Cell-derived Extracellular Matrix Enables Survival and Multi-Lineage Differentiation within Superporous Hydrogels. Biomacromolecules, 13(4): 963-973, 2012. DOI & Pubmed
  24. Rayahin JE, Buhrman JS, Gemeinhart RA. Hybrid Nanocrystals: University of Kentucky US 2006/0280680A1, Expert Opinion on Therapeutic Patents, 22(3): 341-348, 2012. DOI & Pubmed
  25. Desai ES, Tang MY, Ross, A, Gemeinhart RA. Macroporous Hydrogel Scaffolds: A Platform for Cell Encapsulation, Biomedical Materials, 7(2): 024108, 2012. DOI & Pubmed
  26. Shafiq MA, Gemeinhart RA, Yue BYJT, Djalilian AR. Decellularized Human Cornea for Reconstructing the Corneal Epithelium and Anterior Stroma, Tissue Engineering, Part C, 18(5): 340-348, 2012. DOI & Pubmed
  27. Zhao RS, Hollis CP, Zhang H, Sun L, Gemeinhart RA, and Li T. Hybrid Nanocrystals: Achieving Concurrent Therapeutic and Bioimaging Functionalities Toward Solid Tumors, Molecular Pharmaceutics, 8(5): 1985-1991, 2011. DOI & Pubmed
  28. Bae M, Divan R, Suthar KJ, Mancini DC, Gemeinhart RA. Fabrication of PEG Hydrogel Particles for Pharmaceutics using Electron beam and Optical Lithography, Journal of Vaccuum Science and Technology-B. 28(6): C6P24-C6P26, 2010. DOI & Pubmed
  29. Kadakia A, Keskar V, Djilian A, Gemeinhart RA, Cho MR. Materials Characterization of Hybrid Superporous Scaffolds, Critical Reviews in Biomedical Engineering. 36(5-6): 441-471, 2008. DOI & Pubmed
  30. Vartak DG, Lee BS, Gemeinhart RA. In vitro evaluation of functional interaction of integrin aνβ3 and matrix metalloprotease-2, Molecular Pharmaceutics, 6(6): 1856-1867, 2009. DOI & Pubmed
  31. Keskar V, Gandhi M, Gemeinhart EJ, Gemeinhart RA. Initial Evaluation of Vascular Ingrowth into Superporous Hydrogels, Journal of Tissue Engineering and Regenerative Medicine 3(6): 486-490, 2009. DOI & Pubmed
  32. Gandhi M, Srikar R, Yarin AL, Megaridis CM, Gemeinhart RA. Mechanistic Examination of Protein Release from Polymer Nanofibers, Molecular Pharmaceutics, 6(2): 641-647, 2009. DOI & Pubmed
  33. Keskar V, Marion NW, Mao JJ, Gemeinhart RA. In Vitro Evaluation of Macroporous Hydrogels to Facilitate Stem Cell Infiltration, Growth and Mineralization. Tissue Engineering, Part A. 15A(7): 1695-1707, 2009. DOI & Pubmed
  34. Gemeinhart RA. Digestive Enzyme Targeted Polymer Therapeutic:  MIT WO 2007/103364 A2. Expert Opinion on Therapeutic Patents. 18(9): 1085-1090, 2008. DOI
  35. Tauro JR, Lee BS, Lateef SS, Gemeinhart RA. Matrix Metalloprotease Selective Platinate Release from Hydrogel Matrices, Peptides. 29(11) 1965-1973, 2008. DOI & Pubmed
  36. Guo C, Gemeinhart RA. Investigation of the mechanism of chitosan adsorption to poly(lactide-co-glycolide) nanoparticles. European Journal of Pharmaceutics and Biopharmaceutics. 70(2): 597-604, 2008. DOI & Pubmed
  37. Chaterji S, Gemeinhart RA. Enhanced Osteoblast-Like Cell Adhesion and Proliferation Using Sulfated Polymeric Scaffold. Journal of Biomedical Materials Reserach. 83A(4): 990-998, 2007. DOI & Pubmed
  38. Vartak DG, Gemeinhart RA. Matrix metalloproteases: Underutilized Targets for Drug Delivery (Invited Review). Journal of Drug Targeting, 15(1): 1-20, 2007. DOI & Pubmed
  39. Keskar V, Mohanty, PS, Gemeinhart EJ, Gemeinhart RA. Development of a local system for treatment of cervical cancer. Journal of Controlled Release 115(3): 280-288, 2006. DOI & Pubmed
  40. Gemeinhart RA, Bare CM, Haasch RT, Gemeinhart EJ. Osteoblast-like cell attachment to and calcification of novel phosphate-containing polymeric substrates. Journal of Biomedical Materials Reserach. 78A(3): 433-440, 2006. DOI & Pubmed
  41. Muni NJ, Qian H, Qtaishat NM, Gemeinhart RA, Pepperberg DR. Activation of membrane receptors by neurotransmitter released from temperature-sensitivehydrogels. Journal of Neuroscience Methods. 151(2): 97-105, 2006. DOI & Pubmed
  42. Tauro JR, Gemeinhart RA. Matrix metalloprotease triggered local delivery of cancer chemotherapeutics from hydrogel matrixes. Bioconjugate Chemistry16(5): 1133-1139, 2005. DOI & Pubmed
  43. Tauro JR, Gemeinhart RA. Extracellular protease activation of chemotherapeutics from hydrogel matrices: A new paradigm for local chemotherapy. Molecular Pharmaceutics 2(5): 435-438, 2005. DOI & Pubmed
  44. Tauro JR, Gemeinhart RA. Development of amine-containing polymeric nanoparticles. Journal of Biomaterials Science, Polymer Edition 16(10): 1233-1244, 2005. DOI & Pubmed
  45. Yan X, Gemeinhart RA. Cisplatin delivery from poly(acrylic acid-co-methyl methacrylate) microparticles. Journal of Controlled Release 106(1-2): 198-208, 2005. DOI & Pubmed
  46. Gemeinhart RA, Luo D, Saltzman WM. Cellular fate of a modular DNA delivery system mediated by silica nanoparticles. Biotechnology Progress 21(2): 532-537, 2005. DOI & Pubmed
  47. Tan J, Gemeinhart RA, Ma M, Saltzman WM. Improved cell adhesion and proliferation on synthetic phosphonic acid-containing hydrogels. Biomaterials 26(17): 3663-3671, 2005. DOI & Pubmed
  48. Kang CE, Gemeinhart EJ,Gemeinhart RA. Celluar alignment by grafted adhesion peptide surface density gradients. Journal of Biomedical Materials Research 71(3): 403-411, 2004. DOI & Pubmed
  49. Guo C, Gemeinhart RA. Assessment of a modular transfection mechanism based upon cellular localization of DNA. Molecular Pharmaceutics 1(4): 309-316, 2004. DOI & Pubmed
  50. Gemeinhart RA, Park H, Park K. Effect of compression on fast swelling of poly(acrylamide-co-acrylic acid) superporous hydrogels. Journal of Biomedical Materials Research 55(1): 54-62, 2001. DOI & Pubmed
  51. Gemeinhart RA, Chen J, Park H, Park K. pH-Sensitivity of fast responsive superporous hydrogels. Journal of Biomaterials Science, Polymer Edition 11(12): 1371-1380, 2000. DOI & Pubmed
  52. Gemeinhart RA, Park H, Park K. Pore structure of superporous hydrogels. Polymers for Advanced Technologies 11(8-12): 617-625, 2000. DOI
  53. Park K, Gemeinhart RA, Park H. Movement of fibrinogen receptors on the ventral membranes of spreading platelets. Biomaterials 19(4-5): 387-395, 1998. DOI & Pubmed
Book Chapters
  1. Zamiri C, Gemeinhart RA. Drug Delivery Systems for Pulmonary Delivery of Therapeutic Biomacromolecules, in Pharmaceutical Biotechnology, Second Edition, Ed. Groves MJ. Boca Raton, FL: CRC Press; 2005, 255-277.
  2. Gemeinhart RA. Polymers for Oral Biomolecule Delivery, in Pharmaceutical Biotechnology, Second Edition, Second Edition, Ed. Groves MJ. Boca Raton, FL: CRC Press; 2005, 279-302.
  3. Gemeinhart RA, Guo C. Fast Swelling Hydrogel Systems, in Reflexive polymers and hydrogels: Understanding and designing fast-responsive polymeric systems, edited by Yui N, Mrsny R, Park K, 2004.
  4. Rayahin JE, Gemeinhart RA. Activation of Macrophages in Response to Biomaterials. In: Kloc M (ed) Macrophages - Origin, functions and biointervention part of the Results and problems in cell differentiation series. Springer, New York. 2017, Volume 62, Chapter 13, 317-351. DOI & Pubmed
  1. Gemeinhart RA, Buhrman JS, Rayahin JE. Hydrogels for Delivery of Therapeutic Polypeptides, US 9,457,101B2 (October 4, 2016). USPTO
  2. Cho MR, Kadakia A, Djilian A, Gemeinhart RA. Hybrid Superporous Hydrogel Scaffold for Cornea Regeneration. Patent Application, 2010/80,840A1 (April 1, 2010). USPTO
  3. Gemeinhart RA. Superporous Hydrogel with Cells Encapsulated Therein and Method for Producing the Same. US 8,414,879B2 (April 9, 2013). USPTO
  4. Gemeinhart RA, Tauro JR. Composition and Method for Providing Localized Delivery of a Therapeutic Agent. US 7,943,569 (May 17, 2011). USPTO
Input Richard A. Gemeinahrt: BPS, College of Pharmacy in Other
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