Publications  Google Scholar | Pubmed | Scopus 

#RefDOIPubmed
57Andrianopoulou A†, Sokolowski K†, Wenzler E, Bulman ZP, Gemeinhart RA. Assessment of antibiotic release and antibacterial efficacy from pendant glutathione hydrogels using ex vivo porcine skin. Journal of Controlled Release, 365(1): 936-949, 2024.10.1016/j.jconrel.2023.12.0083807060
56Dial CF, Gemeinhart RA. Biophysical Characterization of Interactions between Serum Albumin and Block Copolymer Micelles. ACS Biomaterials Science and Engineering 8(7): 2899-2907, 2022.10.1021/acsbiomaterials.2c0001635767337
55Sokolowski K, Pham H, Wenzler E, Gemeinhart RA. Glutathione Conjugated Hydrogels: Smart, Flexible Vehicles for Personalized Treatment of Bacterial Infections. Pharmaceutical Research 38(7): 1247-1261, 2021.10.1007/s11095-021-03057-134117588
54Langridge TD, Gemeinhart RA. Toward Understanding Polymer Micelle Stability: Density Ultracentrifugation Offers Insight into Polymer Micelle Stability in Human Fluids. Journal of Controlled Release 319(1): 157-167, 2020.10.1016/j.jconrel.2019.12.03834117588
53Liu Y, Zhang Y, Chen S-N, Friesen JB, Nikolic D, Choules MP, McAlpine JB, Lankin DC, Gemeinhart RA, Pauli GF. The Influence of Natural Deep Eutectic Solvents on Bioactive Natural Products: Studying Interactions between a Hydrogel Model and Schisandra chinensisMetabolites. Fitoterapia 127: 212-219, 2018.10.1016/j.fitote.2018.02.02429474979
52Zhang Y, Buhrman JS, Liu Y, Rayahin JE, Gemeinhart RA. Reducible Micelleplexes are Stable Systems for Anti-miRNA Delivery in Cerebrospinal Fluid. Molecular Pharmaceutics 13(6): 1791-1799, 2016.10.1021/acs.molpharmaceut.5b0093327177352
51Jaishankar D†, Buhrman JS†, Valyi-Nagy T,Gemeinhart RA, Shukla D. Extended release of an anti-heparan sulfate peptide from a contact lens suppresses corneal Herpes Simplex Virus-1 (HSV-1) infection. Investigative Ophthalmology and Visual Science 57(1): 169-180, 2016.10.1167/iovs.15-1836526780322
50Lu Y, Chen Y, Gemeinhart RA, Wu W, Li T. Developing nanocrystals for cancer treatment. Nanomedicine 10(16): 2537-2552, 2015.10.2217/nnm.15.7326293310
49Rayahin JE, Buhrman JS, Zhang Y, Koh TJ, Gemeinhart RA. High and low molecular weight hyaluronic acid differentially influence macrophage activation. ACS Biomaterials Science and Engineering 1(7): 481-493, 2015.10.1021/acsbiomaterials.5b0018126280020
48Zhang Y, Liu Y Sen S, Král P, Gemeinhart RA. Charged Group Surface Accessibility Determines Micelleplexes Formation and Cellular Interaction. Nanoscale 7(17): 7559-7564, 2015.10.1039/C5NR00095E25866141
47Rayahin JE, Buhrman JS, Gemeinhart RA. Melittin, as a glutathione S-transferase fusion protein, maintains anti-inflammatory properties while diminishing toxicity. European Journal of Pharmaceutical Sciences 65(1): 112-121, 2014.10.1016/j.ejps.2014.09.01225240321
46Zhang Y, Köllmer M, Buhrman JS, Tang MY, Gemeinhart RA. Arginine-rich, Cell Penetrating Peptide-microRNA Inhibitor Complexes Decrease Glioblastoma Migration Potential. Peptides 58(1): 83-90, 2014.10.1016/j.peptides.2014.06.00824969623
45Zellander A, Zhao H, Kotecha M, Low, K-B, Gemeinhart RA, Wardlow M, Abiade J, Cho M. Characterization of pore structure in biologically functional Poly(2-hydroxyethyl methacrylate)-poly(ethylene glycol) diacrylate (PHEMA-PEGDA). PLOS One 9(5): e96709, 2014.10.1371/journal.pone.009670924816589
44Sharma V, Köllmer M, Szymusiak M, Nitsche LC, Gemeinhart RA, Liu Y. Toroidal-spiral particles for co-delivery of anti-VEGFR-2 antibody and irinotecan-a potential implant to hinder recurrence of glioblastoma multiforme. Biomacromolecules 15(3): 756-762, 2014.10.1021/bm401550r 24460101
43Zhang H, Wang X, Dai W,Gemeinhart RA, Zhang Q, Li T. Pharmacokinetics and Treatment Efficacy of Camptothecin Nanocrystals on Lung Metastasis. Molecular Pharmaceutics 11(1): 226-233, 2013.10.1021/mp400401824294887
42Zhang Y, Wang ZJ, Gemeinhart RA. Progress in MicroRNA Delivery. Journal of Controlled Release172(3): 962-974, 2013.10.1016/j.jconrel.2013.09.01524075926
41Buhrman JS, Cook LC, Rayahin JE, Federle MJ, Gemeinhart RA. Active, soluble recombinant melittin purified by extracting insoluble lysate of Escherichia coli without denaturation. Biotechnology Progress 29(5): 1150-1157, 2013.10.1002/btpr.178423926061
40Köllmer M, Popescu C, Manda P, Zhou L, Gemeinhart RA. Stability of Benzocaine Formulated in Commercial Oral Disintegrating Tablet Platforms. AAPS PharmSciTech 14(4): 1333-1340, 2013.10.1208/s12249-013-0015-523990120
39Hollis CP, Weiss HL, Leggas M, Evers BM, Gemeinhart RA, Li T. Biodistribution and bioimaging studies of hybrid paclitaxel nanocrystals: Lessons learned of the EPR effect and image-guided drug delivery. Journal of Controlled Release 172(1): 12-21, 2013.10.1016/j.jconrel.2013.06.0323920039
38Buhrman JS, Cook LC, Rayahin JE, Federle MJ,Gemeinhart RA. Proteolytically activated anti-bacterial hydrogel microspheres. Journal of Controlled Release 171(3): 288-295.10.1016/j.jconrel.2013.06.02323816641
37Hollis CP, Weiss HL, Evers BM, Gemeinhart RA, Li T. In VivoInvestigation of Hybrid Paclitaxel Nanocrystals with Dual Fluorescent Probes for Cancer Theranostics. Pharmaceutical Research 31(6): 1450-1459, 2014.10.1007/s11095-013-1048-x 23619595
36Köllmer M, Buhrman JS, Zhang Y, Gemeinhart RA. Markers Are Shared Between Adipogenic and Osteogenic Differentiated Mesenchymal Stem Cells. Journal of Developmental Biology and Tissue Engineering 5(2): 18-25, 2013.10.5897/JDBTE2013.006524013643
35Zellander A,Gemeinhart RA, Djalilian AR, Makhsous M, Sun S, Cho MR. Desiging a Gas Foamed Scaffold for Keratoprosthesis. Material Science and Engineering C-Materials for Biological Applications 33(6): 3396-3406, 2013.10.1016/j.msec.2013.04.02523706226
34Buhrman JS, Rayahin JE, Köllmer M, Gemeinhart RA. In-house preparation of hydrogels for batch affinity purification of glutathione S-transferase tagged recombinant proteins. BMC Biotechnology 12(1): 63, 2012.10.1186/1472-6750-12-6322989306
33Ross AE, Tang MY, Gemeinhart RA. Effects of Molecular Weight and Loading on Matrix Metalloproteinase-2 Mediated Release from Poly(Ethylene Glycol) Diacrylate Hydrogels. The AAPS Journal 14(3): 482-490, 2012. 10.1208/S12248-012-9356-322535508
32Zhang Y, Gemeinhart RA. Improving Matrix Metalloproteinase-2 Specific Response of a Hydrogel System using Electrophoresis. International Journal of Pharmaceutics 429(1-2): 31-37, 2012.10.1016/j.ijpharm.2012.03.01222440150
31Köllmer M, Keskar V, Hauk TG, Collins JM, Russell B, Gemeinhart RA. Stem Cell-derived Extracellular Matrix Enables Survival and Multi-Lineage Differentiation within Superporous Hydrogels. Biomacromolecules 13(4): 963-973, 2012.10.1021/bm300332w22404228
30Rayahin JE, Buhrman JS, Gemeinhart RA. Hybrid Nanocrystals: University of Kentucky US 2006/0280680A1. Expert Opinion on Therapeutic Patents 22(3): 341-348, 2012.10.1517/13543776.2012.66587722364361
29Desai ES, Tang MY, Ross, A, Gemeinhart RA. Macroporous Hydrogel Scaffolds: A Platform for Cell Encapsulation. Biomedical Materials 7(2): 024108, 2012.10.1088/1748-6041/7/2/02410822455976
28Shafiq MA, Gemeinhart RA, Yue BYJT, Djalilian AR. Decellularized Human Cornea for Reconstructing the Corneal Epithelium and Anterior Stroma. Tissue Engineering, Part C 18(5): 340-348, 2012.10.1089/ten.TEC.2011.007222082039
27Zhao RS, Hollis CP, Zhang H, Sun L, Gemeinhart RA, and Li T. Hybrid Nanocrystals: Achieving Concurrent Therapeutic and Bioimaging Functionalities Toward Solid Tumors. Molecular Pharmaceutics 8(5): 1985-1991, 2011.10.1021/mp200154k 21812439
26Bae M, Divan R, Suthar KJ, Mancini DC, Gemeinhart RA. Fabrication of PEG Hydrogel Particles for Pharmaceutics using Electron beam and Optical Lithography. Journal of Vaccuum Science and Technology-B 28(6): C6P24-C6P26, 2010.10.1116/1.351771621423572
25Kadakia A, Keskar V, Djilian A, Gemeinhart RA, Cho MR. Materials Characterization of Hybrid Superporous Scaffolds. Critical Reviews in Biomedical Engineering 36(5-6): 441-471, 2008.10.1615/CritRevBiomedEng.v36.i5-6.5020092432
24Vartak DG, Lee BS, Gemeinhart RA. In vitro evaluation of functional interaction of integrin aVβ3 and matrix metalloprotease-2. Molecular Pharmaceutics 6(6): 1856-1867, 2009.10.1021/mp900152t 19799453
23Keskar V, Gandhi M, Gemeinhart EJ, Gemeinhart RA. Initial Evaluation of Vascular Ingrowth into Superporous Hydrogels. Journal of Tissue Engineering and Regenerative Medicine 3(6): 486-490, 2009.10.1002/term.1819526620
22Gandhi M, Srikar R, Yarin AL, Megaridis CM, Gemeinhart RA. Mechanistic Examination of Protein Release from Polymer Nanofibers. Molecular Pharmaceutics 6(2): 641-647, 2009.10.1021/mp800160p 19718809
21Keskar V, Marion NW, Mao JJ, Gemeinhart RA. In VitroEvaluation of Macroporous Hydrogels to Facilitate Stem Cell Infiltration, Growth and Mineralization. Tissue Engineering, Part A 15A(7): 1695-1707, 2009.10.1089/ten.tea.2008.023819119921
20Gemeinhart RA. Digestive Enzyme Targeted Polymer Therapeutic: MIT WO 2007/103364 A2. Expert Opinion on Therapeutic Patents 18(9): 1085-1090, 2008.10.1517/13543776.18.9.1085 
19Tauro JR, Lee BS, Lateef SS, Gemeinhart RA. Matrix Metalloprotease Selective Platinate Release from Hydrogel Matrices. Peptides 29(11) 1965-1973, 2008.10.1016/j.peptides.2008.06.0211865286
18Guo C, Gemeinhart RA. Investigation of the mechanism of chitosan adsorption to poly(lactide-co-glycolide) nanoparticles. European Journal of Pharmaceutics and Biopharmaceutics 70(2): 597-604, 2008.10.1016/j.ejpb.2008.06.00818602994
17Chaterji S, Gemeinhart RA. Enhanced Osteoblast-Like Cell Adhesion and Proliferation Using Sulfated Polymeric Scaffold. Journal of Biomedical Materials Research 83A(4): 990-998, 2007.10.1002/jbm.a.3128317584889
16Vartak DG, Gemeinhart RA. Matrix metalloproteases: Underutilized Targets for Drug Delivery (Invited Review). Journal of Drug Targeting 15(1): 1-20, 2007. 10.1080/1061186060096896717365270
15Keskar V, Mohanty, PS, Gemeinhart EJ, Gemeinhart RA. Development of a local system for treatment of cervical cancer. Journal of Controlled Release 115(3): 280-288, 2006.10.1016/j.jconrel.2006.08.01417034891
14Gemeinhart RA, Bare CM, Haasch RT, Gemeinhart EJ. Osteoblast-like cell attachment to and calcification of novel phosphate-containing polymeric substrates. Journal of Biomedical Materials Research 78A(3): 433-440, 2006. 10.1002/jbm.a.3078816955553
13Muni NJ, Qian H, Qtaishat NM, Gemeinhart RA, Pepperberg DR. Activation of membrane receptors by neurotransmitter released from temperature-sensitivehydrogels. Journal of Neuroscience Methods 151(2): 97-105, 2006.10.1016/j.jneumeth.2005.06.02916198001
12Tauro JR, Gemeinhart RA. Matrix metalloprotease triggered local delivery of cancer chemotherapeutics from hydrogel matrixes. Bioconjugate Chemistry 16(5): 1133-1139, 2005.10.1021/bc050130316173790
11Tauro JR, Gemeinhart RA. Extracellular protease activation of chemotherapeutics from hydrogel matrices: A new paradigm for local chemotherapy. Molecular Pharmaceutics 2(5): 435-438, 2005.10.1021/mp050028n16196497
10Tauro JR, Gemeinhart RA. Development of amine-containing polymeric nanoparticles. Journal of Biomaterials Science, Polymer Edition 16(10): 1233-1244, 2005.10.1163/15685620577426953916268250
9Yan X, Gemeinhart RA. Cisplatin delivery from poly(acrylic acid-co-methyl methacrylate) microparticles. Journal of Controlled Release 106(1-2): 198-208, 2005.10.1016/j.jconrel.2005.05.00515979187
8Gemeinhart RA, Luo D, Saltzman WM. Cellular fate of a modular DNA delivery system mediated by silica nanoparticles. Biotechnology Progress 21(2): 532-537, 2005.10.1021/bp049648w15801794
7Tan J, Gemeinhart RA, Ma M, Saltzman WM. Improved cell adhesion and proliferation on synthetic phosphonic acid-containing hydrogels. Biomaterials 26(17): 3663-3671, 2005.10.1016/j.biomaterials.2004.09.05315621257
6Kang CE, Gemeinhart EJ,Gemeinhart RA. Celluar alignment by grafted adhesion peptide surface density gradients. Journal of Biomedical Materials Research 71(3): 403-411, 2004.10.1002/jbm.a.3013715481057
5Guo C, Gemeinhart RA. Assessment of a modular transfection mechanism based upon cellular localization of DNA. Molecular Pharmaceutics 1(4): 309-316, 2004.10.1021/mp049969a15981590
4Gemeinhart RA, Park H, Park K. Effect of compression on fast swelling of poly(acrylamide-co-acrylic acid) superporous hydrogels. Journal of Biomedical Materials Research 55(1): 54-62, 2001.10.1002/1097-4636(200104)55:13.0.co;2-y11426398
3Gemeinhart RA, Chen J, Park H, Park K. pH-Sensitivity of fast responsive superporous hydrogels. Journal of Biomaterials Science, Polymer Edition 11(12): 1371-1380, 2000.10.1163/15685620074439011261878
2Gemeinhart RA, Park H, Park K. Pore structure of superporous hydrogels. Polymers for Advanced Technologies 11(8-12): 617-625, 2000.10.1002/1099-1581(200008/12)11:8/12%3C617::AID-PAT12%3E3.0.CO;2-L 
1Park K, Gemeinhart RA, Park H. Movement of fibrinogen receptors on the ventral membranes of spreading platelets. Biomaterials 19(4-5): 387-395, 1998.10.1016/S0142-9612(97)00111-79677152
  1. Zamiri C, Gemeinhart RA. Drug Delivery Systems for Pulmonary Delivery of Therapeutic Biomacromolecules, in Pharmaceutical Biotechnology, Second Edition, Ed. Groves MJ. Boca Raton, FL: CRC Press; 2005, 255-277.
  2. Gemeinhart RA. Polymers for Oral Biomolecule Delivery, in Pharmaceutical Biotechnology, Second Edition, Second Edition, Ed. Groves MJ. Boca Raton, FL: CRC Press; 2005, 279-302.
  3. Gemeinhart RA, Guo C. Fast Swelling Hydrogel Systems, in Reflexive polymers and hydrogels: Understanding and designing fast-responsive polymeric systems, edited by Yui N, Mrsny R, Park K, 2004.
  4. Rayahin JE, Gemeinhart RA. Activation of Macrophages in Response to Biomaterials. In: Kloc M (ed) Macrophages – Origin, functions and biointervention part of the Results and problems in cell differentiation series. Springer, New York. 2017, Volume 62, Chapter 13, 317-351. DOI & Pubmed
  1. Gemeinhart RA, Buhrman JS, Rayahin JE. Hydrogels for Delivery of Therapeutic Polypeptides, US 9,457,101B2 (October 4, 2016). USPTO
  2. Cho MR, Kadakia A, Djilian A, Gemeinhart RA. Hybrid Superporous Hydrogel Scaffold for Cornea Regeneration. Patent Application, 2010/80,840A1 (April 1, 2010). USPTO
  3. Gemeinhart RA. Superporous Hydrogel with Cells Encapsulated Therein and Method for Producing the Same. US 8,414,879B2 (April 9, 2013). USPTO
  4. Gemeinhart RA, Tauro JR. Composition and Method for Providing Localized Delivery of a Therapeutic Agent. US 7,943,569 (May 17, 2011). USPTO